Metrics details. Childhood sarcoidosis is a rare multisystemic granulomatous disorder of unknown etiology. In the pediatric series reported from the southeastern United States, sarcoidosis had a higher incidence among African Americans. Most reported childhood cases have occurred in patients aged 13—15 years. A persistent, poorly degradable antigen driven cell-mediated immune response leads to a cytokine cascade, to granuloma formation, and eventually to fibrosis.
Childhood sarcoidosis: A rare but fascinating disorder | Pediatric Rheumatology | Full Text
Metrics details. BD is a systemic inflammatory disease with a variable vasculitis. Paediatric onset is very rare and carries a strong genetic component. Oral ulcers and fever of unknown origin are frequent at onset and difficult to distinguish from other inflammatory disorders; therefore, expert opinion is still mandatory to recognize the disease early.
Very young asian teen ped. The condition causes inflammation in the blood vessels, and the symptoms can be severe. Children develop high fever for several days, rash, swollen neck glands, swollen hands and feet, and red eyes, lips, and tongue.