Subcutaneous facial fat loss

Head of the Department: Prof. Facial lipoatrophy refers to the loss of subcutaneous fat tissue presenting by flattening or indentation of convex contour of the face. Facial lipoatrophy is a feature of the normal ageing process. It may be also a manifestation of chronic diseases, most frequently it affects HIV-infected individuals treated with highly active antiretroviral therapy HAART and may constitute a complication of connective tissue diseases, like lupus erythematosus profundus or morphea. Early recognition and treatment of the active stage of connective tissue diseases is of essential significance in prevention of subsequent scarring and atrophy lesions. Esthetic correction of facial lipoatrophy in chronic diseases is a great challenge.
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Facial Wasting

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Role of adipose tissue in facial aging

Age-dependent modification of the facial subcutaneous white adipose tissue sWAT connected with reduction of its volume, modification of collagen content and adhesion between dermal and adipose layers can significantly influence mechanical stability of the skin and cause the development of aging symptoms such as wrinkles. Typical aging appearance in facial skin is at least partly connected with special phenotypical features of facial preadipocytes and mature adipocytes. In this paper, we have discussed the possible roles of local inflammation, compartmental structure of facial sWAT and trans-differentiation processes such as beiging of white adipocytes and adipocyte-myofibroblast transition in facial skin aging. It is widely accepted that skin stiffness, which is one of the main mechanical parameters defining the skin appearance, is continuously reduced in aging skin.
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Role of adipose tissue in facial aging

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Lipodystrophy also called lipoatrophy usually infers loss of fat. Loss of subcutaneous fat leads to an increased definition of the structures underneath muscle and bone and presents as one or more depressions in the skin. If all the underlying structures are affected, it is called panatrophy. Lipodystrophy may be congenital the tendency to lose fat is present at birth or acquired the loss of fat occurs later in life.
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Comments
  •   Nelrajas December 12, 2017
    I just want you to ride this face so I can taste that nut
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    No problem, just do what you want. If you are afraid, do it anyway. What's the worst that can happen?
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    Good! ^^
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